XAging well with a little wine and a good clock

William J. Belden, Jay C. Dunlap

Research output: Contribution to journalShort surveypeer-review

7 Scopus citations

Abstract

Age-related decline in mammalian circadian rhythm has been recognized for decades, but the underlying molecular mechanisms have remained elusive. In this issue of Cell, Chang and Guarente use brain-specific SIRT1 knockout mice and transgenic mice overexpressing SIRT1 to develop an enticing model for how SIRT1 helps maintain the robustness of the aging circadian clock.

Original languageEnglish (US)
Pages (from-to)1421
Number of pages1
JournalCell
Volume153
Issue number7
DOIs
StatePublished - Jun 20 2013

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

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