Xenobiotic-induced liver injury is a clinically important etiology of hepatic disease that, if not recognized, can lead to hepatic failure. In this article we discuss the mechanisms of xenobiotic-induced liver injury, various factors that can alter the risk and severity of injury, the clinical and laboratory manifestations of injury, and the methods used to detect the presence of injury and (or) functioning liver mass.
All Science Journal Classification (ASJC) codes
- Clinical Biochemistry
- Biochemistry, medical
- Ccytochrome P450 enzymes
- Cytotoxic/cholestatic liver injury
- Liver function tests
- Xenobiotic metabolism