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Zinc fingers: DNA binding and protein-protein interactions

Research output: Contribution to journalArticlepeer-review

Abstract

The zinc finger domain is a very ubiquitous structural element whose hallmark is the coordination of a zinc atom by several amino acid residues (cysteines and histidines, and occasionally aspartate and glutamate). These structural elements are associated with protein-nucleic acid recognition as well as protein-protein interactions. The purpose of this review is to examine recent data on the DNA and protein binding properties of a few zinc fingers whose three dimensional structure is known.

Original languageEnglish (US)
Pages (from-to)21-30
Number of pages10
JournalBiological Research
Volume33
Issue number1
DOIs
StatePublished - 2000

All Science Journal Classification (ASJC) codes

  • General Biochemistry, Genetics and Molecular Biology
  • General Agricultural and Biological Sciences

Keywords

  • DNA binding
  • Protein-protein interactions
  • Zinc fingers

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